Location: US 45 and I-22, Tupelo Reassurance shield after the I-22 interchange. Location: US 45 and Barnes Crossing Rd, Tupelo Reassurance shield as we head out of Tupelo. Location: US 45 and MS 145, Saltillo In a mile we’ll approach MS 145. Location: US 45 and MS 145, Saltillo Exit for 145 north and south. … Continue reading U.S. Route 45, I-22/US-78 to MS-145